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Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells.

Double-strand breaks (DSBs) stimulate chromosomal and extrachromosomal recombination and gene targeting. Transcription also stimulates spontaneous recombination by an unknown mechanism. We used Saccharomyces cerevisiae I-SceI to stimulate recombination between neo direct repeats in Chinese hamster o...

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Bibliografische gegevens
Hoofdauteurs: Taghian, D G, Nickoloff, J A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1997
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC232490/
https://ncbi.nlm.nih.gov/pubmed/9343400
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