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Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosis.

Polycomb (Pc) is involved in the stable and heritable repression of homeotic gene activity during Drosophila development. Here, we report the identification of a novel human Pc homolog, hPc2. This gene is more closely related to a Xenopus Pc homolog, XPc, than to a previously described human Pc homo...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Satijn, D P, Olson, D J, van der Vlag, J, Hamer, K M, Lambrechts, C, Masselink, H, Gunster, M J, Sewalt, R G, van Driel, R, Otte, A P
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1997
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232457/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9315667/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.10.6076
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