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Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosis.

Polycomb (Pc) is involved in the stable and heritable repression of homeotic gene activity during Drosophila development. Here, we report the identification of a novel human Pc homolog, hPc2. This gene is more closely related to a Xenopus Pc homolog, XPc, than to a previously described human Pc homo...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Satijn, D P, Olson, D J, van der Vlag, J, Hamer, K M, Lambrechts, C, Masselink, H, Gunster, M J, Sewalt, R G, van Driel, R, Otte, A P
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232457/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9315667/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.10.6076
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