Tissue transglutaminase-dependent posttranslational modification of the retinoblastoma gene product in promonocytic cells undergoing apoptosis.

The retinoblastoma gene product (pRB) plays an important role in controlling both cell release from the G1 phase and apoptosis. We show here that in the early phases of apoptosis, pRB is posttranslationally modified by a tissue transglutaminase (tTG)-catalyzed reaction. In fact, by employing a novel...

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Bibliografiske detaljer
Main Authors: Oliverio, S, Amendola, A, Di Sano, F, Farrace, M G, Fesus, L, Nemes, Z, Piredda, L, Spinedi, A, Piacentini, M
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC232453/
https://ncbi.nlm.nih.gov/pubmed/9315663
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