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Discrete restraint-based protein modeling and the Cα-trace problem

We present a novel de novo method to generate protein models from sparse, discretized restraints on the conformation of the main chain and side chain atoms. We focus on Cα-trace generation, the problem of constructing an accurate and complete model from approximate knowledge of the positions of the...

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Autori principali: DePristo, Mark A., de Bakker, Paul I.W., Shetty, Reshma P., Blundell, Tom L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323999/
https://ncbi.nlm.nih.gov/pubmed/12931001
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