Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity

The spike (S) protein of SARS coronavirus (SARS-CoV) has been known to recognize and bind to host receptors, whose conformational changes then facilitate fusion between the viral envelope and host cell membrane, leading to viral entry into target cells. However, other functions of SARS-CoV S protein...

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Bibliographic Details
Main Authors: Du, Lanying, Kao, Richard Y., Zhou, Yusen, He, Yuxian, Zhao, Guangyu, Wong, Charlotte, Jiang, Shibo, Yuen, Kwok-Yung, Jin, Dong-Yan, Zheng, Bo-Jian
Format: Artigo
Language:Inglês
Published: Elsevier Inc. 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323977/
https://ncbi.nlm.nih.gov/pubmed/17533109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.05.092
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