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Fast protein folding on downhill energy landscape

Proteins fold in a time range of microseconds to minutes despite the large amount of possible conformers. Molecular dynamics simulations of a three-stranded antiparallel β-sheet peptide (for a total of 12.6 μsec and 72 folding events) show that at the melting temperature the unfolded state ensemble...

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Detalhes bibliográficos
Main Authors: Cavalli, Andrea, Haberthür, Urs, Paci, Emanuele, Caflisch, Amedeo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323966/
https://ncbi.nlm.nih.gov/pubmed/12876329
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