Conformational changes induced in Hoxb-8/Pbx-1 heterodimers in solution and upon interaction with specific DNA.

Two classes of homeodomain proteins, Hox and Pbx gene products, have the ability to bind cooperatively to DNA. In Hox proteins, the homeodomain and a highly conserved hexapeptide are required for cooperative DNA binding. In Pbx, the homeodomain and a region immediately C terminal of the homeodomain...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Sánchez, M, Jennings, P A, Murre, C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232387/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9271414/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.9.5369
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