Requirement of protein kinase C zeta for stimulation of protein synthesis by insulin.
The ability of insulin to stimulate protein synthesis and cellular growth is mediated through the insulin receptor (IR), which phosphorylates Tyr residues in the insulin receptor substrate-signaling proteins (IRS-1 and IRS-2), Gab-1, and Shc. These phosphorylated substrates directly bind and activat...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
1997
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232369/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9271396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.9.5184 |
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