Requirement of protein kinase C zeta for stimulation of protein synthesis by insulin.
The ability of insulin to stimulate protein synthesis and cellular growth is mediated through the insulin receptor (IR), which phosphorylates Tyr residues in the insulin receptor substrate-signaling proteins (IRS-1 and IRS-2), Gab-1, and Shc. These phosphorylated substrates directly bind and activat...
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| Gepubliceerd in: | Mol Cell Biol |
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| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis
1997
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232369/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9271396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.9.5184 |
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