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Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: Role of NMDA receptor activation and NMDA dependent calcium entry

The hippocampus is especially vulnerable to seizure-induced damage and excitotoxic neuronal injury. This study examined the time course of neuronal death in relationship to seizure duration and the pharmacological mechanisms underlying seizure-induced cell death using low magnesium (Mg(2+)) induced...

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Bibliografiske detaljer
Main Authors: Deshpande, Laxmikant S., Lou, Jeffrey K., Mian, Ali, Blair, Robert E., Sombati, Sompong, Attkisson, Elisa, DeLorenzo, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323609/
https://ncbi.nlm.nih.gov/pubmed/18289526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2008.01.025
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