Zinc Binding Ligands and Cellular Zinc Trafficking: Apo-metallothionein, Glutathione, TPEN, Proteomic Zinc, and Zn-Sp1

Many cell types contain metal-ion unsaturated metallothionein (MT). Considering the Zn(2+) binding affinity of metallothionein, the existence of this species in the intracellular environment constitutes a substantial “thermodynamic sink.” Indeed, the mM concentration of glutathione may be thought of...

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Bibliografiske detaljer
Main Authors: Rana, Ujala, Kothinti, Rajendra, Meeusen, Jeffrey, Tabatabai, Niloofar M., Krezoski, Susan, Petering, David H.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323593/
https://ncbi.nlm.nih.gov/pubmed/18171589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2007.10.030
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