Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

Innate immunity is critically dependent on the rapid production of interferon in response to intruding viruses. The intracellular pathogen recognition receptors RIG-I and MDA5 are essential for interferon induction by viral RNAs containing 5′ triphosphates or double-stranded structures, respectively...

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Detalhes bibliográficos
Main Authors: Habjan, Matthias, Andersson, Ida, Klingström, Jonas, Schümann, Michael, Martin, Arnold, Zimmermann, Petra, Wagner, Valentina, Pichlmair, Andreas, Schneider, Urs, Mühlberger, Elke, Mirazimi, Ali, Weber, Friedemann
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323571/
https://ncbi.nlm.nih.gov/pubmed/18446221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002032
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