Correlation of Memory T Cell Responses against TRAP with Protection from Clinical Malaria, and CD4(+) CD25(high) T Cells with Susceptibility in Kenyans

BACKGROUND: Immunity to malaria develops naturally in endemic regions, but the protective immune mechanisms are poorly understood. Many vaccination strategies aim to induce T cells against diverse pre-erythrocytic antigens, but correlates of protection in the field have been limited. The objective o...

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Detalhes bibliográficos
Main Authors: Todryk, Stephen M., Bejon, Philip, Mwangi, Tabitha, Plebanski, Magdalena, Urban, Britta, Marsh, Kevin, Hill, Adrian V. S., Flanagan, Katie L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323567/
https://ncbi.nlm.nih.gov/pubmed/18446217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002027
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