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Clearing asymptomatic parasitaemia increases the specificity of the definition of mild febrile malaria

In clinical trials, the specificity of the disease endpoint is critical to an accurate estimate of vaccine efficacy. We used a logistic regression model to analyse parasite densities among children before and after treatment with antimalarials, in order to estimate the impact that clearing asymptoma...

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Detalhes bibliográficos
Main Authors: Bejon, Philip, Mwangi, Tabitha, Lowe, Brett, Peshu, Norbert, Hill, Adrian V.S., Marsh, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702749/
https://ncbi.nlm.nih.gov/pubmed/17950960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.07.057
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