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Clearing asymptomatic parasitaemia increases the specificity of the definition of mild febrile malaria

In clinical trials, the specificity of the disease endpoint is critical to an accurate estimate of vaccine efficacy. We used a logistic regression model to analyse parasite densities among children before and after treatment with antimalarials, in order to estimate the impact that clearing asymptoma...

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Détails bibliographiques
Auteurs principaux: Bejon, Philip, Mwangi, Tabitha, Lowe, Brett, Peshu, Norbert, Hill, Adrian V.S., Marsh, Kevin
Format: Artigo
Langue:Inglês
Publié: Elsevier Science 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702749/
https://ncbi.nlm.nih.gov/pubmed/17950960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.07.057
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