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Synthesis and antibacterial activity of hydrolytically stable (–)-epicatechin gallate analogues for the modulation of β-lactam resistance in Staphylococcus aureus
Hydrolytically more stable analogues of (–)-epicatechin gallate (ECg) have been synthesised from ECg where an amine or amide function has been substituted for the ester linkage that joins the C-ring with the galloyl D-ring. Sub-inhibitory concentrations (25 mg/L) of the amide analogue 7, possessing...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323490/ https://ncbi.nlm.nih.gov/pubmed/15863332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2005.03.063 |
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