Synthesis and antibacterial activity of hydrolytically stable (–)-epicatechin gallate analogues for the modulation of β-lactam resistance in Staphylococcus aureus

Hydrolytically more stable analogues of (–)-epicatechin gallate (ECg) have been synthesised from ECg where an amine or amide function has been substituted for the ester linkage that joins the C-ring with the galloyl D-ring. Sub-inhibitory concentrations (25 mg/L) of the amide analogue 7, possessing...

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Hlavní autoři: Anderson, James C., Headley, Catherine, Stapleton, Paul D., Taylor, Peter W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323490/
https://ncbi.nlm.nih.gov/pubmed/15863332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2005.03.063
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