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Central blockade of melanocortin receptors attenuates the metabolic and locomotor responses to peripheral IL-1β administration
Loss of appetite and cachexia is an obstacle in the treatment of chronic infection and cancer. Proinflammatory cytokines released from activated immune cells and acting in the central nervous system (CNS) are prime candidates for mediating these metabolic changes, potentially affecting both energy i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323450/ https://ncbi.nlm.nih.gov/pubmed/18082228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2007.10.014 |
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