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The central melanocortin system directly controls peripheral lipid metabolism

Disruptions of the melanocortin signaling system have been linked to obesity. We investigated a possible role of the central nervous melanocortin system (CNS-Mcr) in the control of adiposity through effects on nutrient partitioning and cellular lipid metabolism independent of nutrient intake. We rep...

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Main Authors: Nogueiras, Ruben, Wiedmer, Petra, Perez-Tilve, Diego, Veyrat-Durebex, Christelle, Keogh, Julia M., Sutton, Gregory M., Pfluger, Paul T., Castaneda, Tamara R., Neschen, Susanne, Hofmann, Susanna M., Howles, Philip N., Morgan, Donald A., Benoit, Stephen C., Szanto, Ildiko, Schrott, Brigitte, Schürmann, Annette, Joost, Hans-Georg, Hammond, Craig, Hui, David Y., Woods, Stephen C., Rahmouni, Kamal, Butler, Andrew A., Farooqi, I. Sadaf, O’Rahilly, Stephen, Rohner-Jeanrenaud, Françoise, Tschöp, Matthias H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978426/
https://ncbi.nlm.nih.gov/pubmed/17885689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31743
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