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Vaccination and Timing Influence SIV Immune Escape Viral Dynamics In Vivo

CD8+ cytotoxic T lymphocytes (CTL) can be effective at controlling HIV-1 in humans and SIV in macaques, but their utility is partly offset by mutational escape. The kinetics of CTL escape and reversion of escape mutant viruses upon transmission to MHC-mismatched hosts can help us understand CTL-medi...

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Detaylı Bibliyografya
Asıl Yazarlar: Loh, Liyen, Petravic, Janka, Batten, C. Jane, Davenport, Miles P, Kent, Stephen J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323283/
https://ncbi.nlm.nih.gov/pubmed/18225952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0040012
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