Pbx raises the DNA binding specificity but not the selectivity of antennapedia Hox proteins.
We have used a binding site selection strategy to determine the optimal binding sites for Pbx proteins by themselves and as heterodimeric partners with various Hox gene products. Among the Pbx proteins by themselves, only Pbx3 binds with high affinity, as a monomer or as a homodimer, to an optimal b...
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| Veröffentlicht in: | Mol Cell Biol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1997
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232322/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234726/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4696 |
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