Platelet CD36 mediates interactions with endothelial cell–derived microparticles and contributes to thrombosis in mice

CD36 is a scavenger receptor that binds multiple ligands, including phosphatidyl serine (PS). Although CD36(–) mice do not have a bleeding diathesis, we show here that they do have significantly prolonged thrombotic occlusion times in response to FeCl(3)-induced vascular injury. Because cell-derived...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ghosh, Arunima, Li, Wei, Febbraio, Maria, Espinola, Ricardo G., McCrae, Keith R., Cockrell, Erin, Silverstein, Roy L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2008
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323190/
https://ncbi.nlm.nih.gov/pubmed/18431509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34904
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