The polypyrimidine tract binding protein binds upstream of neural cell-specific c-src exon N1 to repress the splicing of the intron downstream.

The neural cell-specific N1 exon of the c-src pre-mRNA is both negatively regulated in nonneural cells and positively regulated in neurons. We previously identified conserved intronic elements flanking N1 that direct the repression of N1 splicing in a nonneural HeLa cell extract. The upstream repres...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Chan, R C, Black, D L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232319/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4667
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!