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The polypyrimidine tract binding protein binds upstream of neural cell-specific c-src exon N1 to repress the splicing of the intron downstream.

The neural cell-specific N1 exon of the c-src pre-mRNA is both negatively regulated in nonneural cells and positively regulated in neurons. We previously identified conserved intronic elements flanking N1 that direct the repression of N1 splicing in a nonneural HeLa cell extract. The upstream repres...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Chan, R C, Black, D L
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232319/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234723/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4667
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