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A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans.

A temperature-sensitive mutation was obtained in Med6p, a component of the mediator complex from the yeast Saccharomyces cerevisiae. The mediator complex has been shown to enable transcriptional activation in vitro. This mutation in Med6p abolished activation of transcription from four of five induc...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Lee, Y C, Min, S, Gim, B S, Kim, Y J
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232315/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234719/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4622
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