A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans.

A temperature-sensitive mutation was obtained in Med6p, a component of the mediator complex from the yeast Saccharomyces cerevisiae. The mediator complex has been shown to enable transcriptional activation in vitro. This mutation in Med6p abolished activation of transcription from four of five induc...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Lee, Y C, Min, S, Gim, B S, Kim, Y J
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232315/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234719/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4622
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