Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicity.

Recent studies have demonstrated that Cbl, the 120-kDa protein product of the c-cbl proto-oncogene, serves as a substrate of a number of receptor-coupled tyrosine kinases and forms complexes with SH3 and SH2 domain-containing proteins, pointing to its role in signal transduction. Based on genetic ev...

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Bibliografische gegevens

Gepubliceerd in:	Mol Cell Biol
Hoofdauteurs:	Bonita, D P, Miyake, S, Lupher, M L, Langdon, W Y, Band, H
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Taylor & Francis 1997
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234717/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4597
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