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Changing Selective Pressure during Antigenic Changes in Human Influenza H3

The rapid evolution of influenza viruses presents difficulties in maintaining the optimal efficiency of vaccines. Amino acid substitutions result in antigenic drift, a process whereby antisera raised in response to one virus have reduced effectiveness against future viruses. Interestingly, while ami...

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Detalhes bibliográficos
Main Authors: Blackburne, Benjamin P., Hay, Alan J., Goldstein, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323114/
https://ncbi.nlm.nih.gov/pubmed/18451985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000058
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