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Primate Lentiviral Vpx Commandeers DDB1 to Counteract a Macrophage Restriction
Primate lentiviruses encode four “accessory proteins” including Vif, Vpu, Nef, and Vpr/Vpx. Vif and Vpu counteract the antiviral effects of cellular restrictions to early and late steps in the viral replication cycle. We present evidence that the Vpx proteins of HIV-2/SIV(SM) promote virus infection...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323106/ https://ncbi.nlm.nih.gov/pubmed/18451984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000057 |
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