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A Conserved Pathway That Controls c-Myc Protein Stability through Opposing Phosphorylation Events Occurs in Yeast

The c-Myc transcription factor is a key regulator of cell proliferation and cell fate decisions. c-Myc overexpression is observed in a variety of human tumors, revealing the importance of maintaining normal levels of c-Myc protein. c-Myc protein stability in mammalian cells is controlled by interdep...

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Detalhes bibliográficos
Main Authors: Escamilla-Powers, Julienne R., Sears, Rosalie C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2322940/
https://ncbi.nlm.nih.gov/pubmed/17192266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M611437200
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