Homologous and Heterologous Desensitization of Capsaicin and Mustard Oil Responses Utilize Different Cellular Pathways in Nociceptors

The Transient Receptor Potential channel subtypes V1 (TRPV1) and A1 (TRPA1) play a critical role in the development of hyperalgesia in inflammatory pain models. Although several studies in animals and humans have demonstrated that capsaicin (CAP), a TRPV1-specific agonist, and mustard oil (MO), a TR...

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Main Authors: Ruparel, Nikita B., Patwardhan, Amol M., Akopian, Armen N., Hargreaves, Kenneth M.
格式: Artigo
語言:Inglês
出版: 2007
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2322862/
https://ncbi.nlm.nih.gov/pubmed/17590514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2007.06.005
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