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On the reaction mechanism of l-lactate oxidase: Quantitative structure-activity analysis of the reaction with para-substituted l-mandelates

The rate constants for reduction of the flavoenzyme, l-lactate oxidase, and a mutant (in which alanine 95 is replaced by glycine), by a series of para-substituted mandelates, in both the 2-(1)H- and 2-(2)H- forms, have been measured by rapid reaction spectrophotometry. In all cases, significant isot...

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Detalhes bibliográficos
Main Authors: Yorita, Kazuko, Janko, Karl, Aki, Kenji, Ghisla, Sandro, Palfey, Bruce A., Massey, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23227/
https://ncbi.nlm.nih.gov/pubmed/9275167
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