The immediate-early gene product Egr-1 regulates the human interleukin-2 receptor beta-chain promoter through noncanonical Egr and Sp1 binding sites.

The interleukin-2 IL-2 receptor beta-chain (IL-2Rbeta) is an essential component of the receptors for IL-2 and IL-15. Although IL-2Rbeta is constitutively expressed by lymphocytes, its expression can be further induced by a number of stimuli, including phorbol 12-myristate 13-acetate (PMA). We have...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Lin, J X, Leonard, W J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232223/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9199305/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.7.3714
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