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The immediate-early gene product Egr-1 regulates the human interleukin-2 receptor beta-chain promoter through noncanonical Egr and Sp1 binding sites.

The interleukin-2 IL-2 receptor beta-chain (IL-2Rbeta) is an essential component of the receptors for IL-2 and IL-15. Although IL-2Rbeta is constitutively expressed by lymphocytes, its expression can be further induced by a number of stimuli, including phorbol 12-myristate 13-acetate (PMA). We have...

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Pubblicato in:Mol Cell Biol
Autori principali: Lin, J X, Leonard, W J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232223/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9199305/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.7.3714
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