Tumor promotion by depleting cells of protein kinase C delta.

Tumor-promoting phorbol esters activate, but then deplete cells of, protein kinase C (PKC) with prolonged treatment. It is not known whether phorbol ester-induced tumor promotion is due to activation or depletion of PKC. In rat fibroblasts overexpressing the c-Src proto-oncogene, the phorbol ester 1...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lu, Z, Hornia, A, Jiang, Y W, Zang, Q, Ohno, S, Foster, D A
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC232195/
https://ncbi.nlm.nih.gov/pubmed/9154841
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