Prebending the estrogen response element destabilizes binding of the estrogen receptor DNA binding domain.

Binding of many eukaryotic transcription regulatory proteins to their DNA recognition sequences results in conformational changes in DNA. To test the effect of altering DNA topology by prebending a transcription factor binding site, we examined the interaction of the estrogen receptor (ER) DNA bindi...

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Bibliographic Details
Main Authors: Kim, J, de Haan, G, Nardulli, A M, Shapiro, D J
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC232170/
https://ncbi.nlm.nih.gov/pubmed/9154816
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