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Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes.

We examined the stability of microsatellites of different repeat unit lengths in Saccharomyces cerevisiae strains deficient in DNA mismatch repair. The msh2 and msh3 mutations destabilized microsatellites with repeat units of 1, 2, 4, 5, and 8 bp; a poly(G) tract of 18 bp was destabilized several th...

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Détails bibliographiques
Auteurs principaux: Sia, E A, Kokoska, R J, Dominska, M, Greenwell, P, Petes, T D
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC232137/
https://ncbi.nlm.nih.gov/pubmed/9111357
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