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Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes.

We examined the stability of microsatellites of different repeat unit lengths in Saccharomyces cerevisiae strains deficient in DNA mismatch repair. The msh2 and msh3 mutations destabilized microsatellites with repeat units of 1, 2, 4, 5, and 8 bp; a poly(G) tract of 18 bp was destabilized several th...

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Publicado en:Mol Cell Biol
Autores principales: Sia, E A, Kokoska, R J, Dominska, M, Greenwell, P, Petes, T D
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1997
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232137/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9111357/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.5.2851
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