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Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes.

We examined the stability of microsatellites of different repeat unit lengths in Saccharomyces cerevisiae strains deficient in DNA mismatch repair. The msh2 and msh3 mutations destabilized microsatellites with repeat units of 1, 2, 4, 5, and 8 bp; a poly(G) tract of 18 bp was destabilized several th...

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Published in:Mol Cell Biol
Main Authors: Sia, E A, Kokoska, R J, Dominska, M, Greenwell, P, Petes, T D
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1997
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232137/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9111357/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.5.2851
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