Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins.
A change in the number of base pairs within a coding sequence can result in a frameshift mutation, which almost invariably eliminates the function of the encoded protein. A frameshift reversion assay with Saccharomyces cerevisiae that can be used to examine the types of insertions and deletions that...
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| Опубликовано в:: | Mol Cell Biol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
1997
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232136/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9111356/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.5.2844 |
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