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Expression of the (recombinant) endogenous immunoglobulin heavy-chain locus requires the intronic matrix attachment regions.

The elements which regulate gene expression have traditionally been identified by their effects on reporter genes which have been transfected into cell lines or animals. It is generally assumed that these elements have a comparable role in expression of the corresponding endogenous locus. Neverthele...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Oancea, A E, Berru, M, Shulman, M J
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232116/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9111336/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.5.2658
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