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The Immunoglobulin Heavy Chain Locus Control Region Increases Histone Acetylation along Linked c-myc Genes

In chromosome translocations characteristic of Burkitt lymphomas (BL) and murine plasmacytomas, c-myc genes become juxtaposed to immunoglobulin heavy-chain (IgH) sequences, resulting in aberrant c-myc transcription. Translocated c-myc alleles that retain the first exon exhibit increased transcriptio...

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Publicat a:Mol Cell Biol
Autors principals: Madisen, Linda, Krumm, Anton, Hebbes, Tim R., Groudine, Mark
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109215/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774645/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6281
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