The Immunoglobulin Heavy Chain Locus Control Region Increases Histone Acetylation along Linked c-myc Genes

In chromosome translocations characteristic of Burkitt lymphomas (BL) and murine plasmacytomas, c-myc genes become juxtaposed to immunoglobulin heavy-chain (IgH) sequences, resulting in aberrant c-myc transcription. Translocated c-myc alleles that retain the first exon exhibit increased transcriptio...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Madisen, Linda, Krumm, Anton, Hebbes, Tim R., Groudine, Mark
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1998
Sujets:	Gene Expression
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774645/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6281
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