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Selection of efficient cleavage sites in target RNAs by using a ribozyme expression library.

Inactivation of gene expression by antisense mechanisms in general and by ribozymes in particular is a powerful technique for studying the function of a gene product. We have designed a strategy for expression of ribozymes, for selection of accessible cleavage sites in target RNAs, and for isolation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lieber, A, Strauss, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC232008/
https://ncbi.nlm.nih.gov/pubmed/7528330
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