Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors.

Glucocorticoids are potent immunosuppressants which work in part by inhibiting cytokine gene transcription. We show here that NF-kappa B, an important regulator of numerous cytokine genes, is functionally inhibited by the synthetic glucocorticoid dexamethasone (DEX). In transfection experiments, DEX...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Scheinman, R I, Gualberto, A, Jewell, C M, Cidlowski, J A, Baldwin, A S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231982/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823959/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.943
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