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Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors.

Glucocorticoids are potent immunosuppressants which work in part by inhibiting cytokine gene transcription. We show here that NF-kappa B, an important regulator of numerous cytokine genes, is functionally inhibited by the synthetic glucocorticoid dexamethasone (DEX). In transfection experiments, DEX...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Scheinman, R I, Gualberto, A, Jewell, C M, Cidlowski, J A, Baldwin, A S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 1995
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231982/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.943
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