Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP.

Activation of phosphatidylinositol 3-kinase (PI3K) and activation of the 70/85-kDa S6 protein kinases (alpha II and alpha I isoforms, referred to collectively as pp70S6k) have been independently linked to the regulation of cell proliferation. We demonstrate that these kinases lie on the same signall...

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Bibliografische gegevens

Gepubliceerd in:	Mol Cell Biol
Hoofdauteurs:	Monfar, M, Lemon, K P, Grammer, T C, Cheatham, L, Chung, J, Vlahos, C J, Blenis, J
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Taylor & Francis 1995
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231963/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7528328/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.1.326
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