Tyrosine phosphorylation of BCR by FPS/FES protein-tyrosine kinases induces association of BCR with GRB-2/SOS.

The human bcr gene encodes a protein with serine/threonine kinase activity, CDC24/dbl homology, a GAP domain, and an SH2-binding region. However, the precise physiological functions of BCR are unknown. Coexpression of BCR with the cytoplasmic protein-tyrosine kinase encoded by the c-fes proto-oncoge...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Maru, Y, Peters, K L, Afar, D E, Shibuya, M, Witte, O N, Smithgall, T E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231961/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7529874/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.835
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