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Effects of butyrate and glucocorticoids on gamma- to beta-globin gene switching in somatic cell hybrids.

Butyrate and its analogs have been shown to induce fetal hemoglobin in humans and primates and in erythroid cell cultures. To obtain insights concerning the cellular mechanisms of butyrate action, we analyzed the effects of butyrate on human globin gene expression in hybrids produced by fusing mouse...

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Detalhes bibliográficos
Main Authors: Zitnik, G, Peterson, K, Stamatoyannopoulos, G, Papayannopoulou, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231953/
https://ncbi.nlm.nih.gov/pubmed/7529873
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