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Position-independent transgene expression mediated by boundary elements from the apolipoprotein B chromatin domain.

The human apolipoprotein B (apoB) gene resides within a 47.5-kb chromatin domain that is flanked by sequences that bind to the nuclear matrix. These matrix attachment regions (MARs) are boundaries between nuclease-sensitive and -resistant chromatin. As domain boundaries are thought to function as in...

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Detalhes bibliográficos
Main Authors: Kalos, M, Fournier, R E
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231934/
https://ncbi.nlm.nih.gov/pubmed/7799927
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