Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line.

The zinc finger transcription factor GATA-1 is essential for erythropoiesis. In its absence, committed erythroid precursors arrest at the proerythroblast stage of development and undergo apoptosis. To study the function of GATA-1 in an erythroid cell environment, we generated an erythroid cell line...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Weiss, M J, Yu, C, Orkin, S H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231889/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032291/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.3.1642
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